Consortium of the Research Training Group SYLOBIO
The consortium is composed of ten subprojects, which are divided into four research domains: Inflammation (subprojects E01-E03), Systemic Interaction (subprojects I01-I03), Regeneration (subprojects R01, R02), and the cross-sectional area of Epidemiology and Systems Biology (subprojects Q01, Q02). In addition, various cooperation partners and associated scientists are involved in the research projects.
Subprojects of the Research Training Group SYLOBIO
To access additional information, please click on the abbreviation of the subproject and the name(s) of the related institution(s).
E01
Effects of metallic wear and corrosion products on inflammatory processes of peri-implant bone tissue cells| Members: | Prof. Dr. Rainer Bader, PD Dr. Anika Jonitz-Heincke |
| Dr. Marie-Luise Sellin | |
| Irem Simsek, M.Sc., Erik Dargel, M.Sc. | |
| Affiliation: | Department of Orthopedics, Biomechanics and Implant Technology Research Laboratory, Rostock University Medical Center |
E02
Influence of metallic wear and corrosion products on inflammation and cell death: deciphering the molecular signaling pathways| Members: | Prof. Dr. Barbara Bröker, |
| Behnaz Alsadat Hosseini, M.Sc. | |
| Institute of Immunology and Transfusion Medicine, Department of Immunology, Greifswald University Medical Center | |
| PD Dr. Matthias Sendler | |
| Department of Medicine A, Forschungscluster III, Greifswald University Medical Center | |
| Dr. Janosch Schoon | |
| Clinic and Polyclinic for Orthopedics and Orthopedic Surgery, Greifswald University Medical Center | |
| Anastasia Tavakina, M.Sc. |
E03
Influence of metallic wear and corrosion products on mesenchymal stem and endothelial cells and relevant bacterial pathogens - effects of an inflammatory environment on differentiation and biofilm formation| Members: | PD Dr. Kirsten Peters, Vanessa Caton, M.Sc. |
| Institute of Cell Biology, Rostock University Medical Center | |
| PD Dr. Tomas Fiedler, Ann Charloth Kuhfahl, M.Sc. | |
| Institute of Medical Microbiology, Virology and Hygiene, Rostock University Medical Center |
I01
Long-term impact of metallic wear-particles on the immune system, the skeleton and on the gut microbiome| Members: | Prof. Dr. Brigitte Müller-Hilke, Bahar Deniz, M.Sc. |
| Affiliation: | Institute of Immunology & Core Facility for Cell Sorting & Cell Analysis, Rostock University Medical Center |
I02
In vitro and in vivo studies to investigate the effects of metallic wear and corrosion products on cardiac function| Members: | Prof. Dr. Robert David, Marie Heilen, M.Sc. |
| Affiliation: | Department of Cardiac Surgery, Reference and Translation Center for Cardiac Stem Cell Therapy (RTC), Rostock University Medical Center |
I03
In vitro and in vivo studies on the effect of metallic wear and corrosion products on the nervous system| Members: | Prof. Dr. Dr. Andreas Hermann, Leonarda Vucic, M.Sc. |
| Affiliation: | Translational Neurodegeneration Section „Albrecht Kossel“, Dept. Neurology, Rostock University Medical Center |
R01
Characterization of combined skin wound dressings with respect to regenerative and toxic properties in vitro and ex vivo| Members: | Prof. Dr. Steffen Emmert, Wieland Milz, M.Sc. |
| Affiliation: | Clinic and Policlinic for Dermatology and Venereology, Rostock University Medical Center |
R02
Development and analysis of polymer matrices with specific biomaterial-cell interaction and delayed release of biologically active substances| Members: | Prof. Dr. Niels Grabow, Selina Schultz, M.Sc. |
| Affiliation: | Institute for Biomedical Engineering, Rostock University Medical Center |
Q1
Investigation of bidirectional inflammation-mediated associations between the presence of joint endoprostheses and periodontal and systemic diseases based on epidemiological studies| Members: | PD Dr. Birte Holtfreter, Mazen Waleed Omar, M.Sc. |
| Affiliation: | Department of Restorative Dentistry, Periodontology, Endodontology, and Preventive and Pediatric Dentistry, Greifswald University Medical Center |
Q2
Modeling inflammatory processes to characterize biomaterial interactions using systems biology approaches| Members: | Prof. Dr. Olaf Wolkenhauer, Dr. Matti van Welzen |
| Affiliation: | Department of Systems Biology and Bioinformatics, University of Rostock |
Research Training Group SYLOBIO cooperation partners
| • | Biomatlab, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway |
| • | Institute for Clinical Chemistry and Laboratory Medicine, Rostock University Hospital Center, Germany |
| • | Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics, University of Greifswald, Germany |
| • | Research Department of the Clinic for Orthopedics, Greifswald University Medical Center, Germany |
